Tori Amos: Piece by Piece by Amos Tori & Powers Ann
Author:Amos, Tori & Powers, Ann [Powers, Ann]
Language: eng
Format: epub
Publisher: Crown Archetype
Published: 2008-12-09T22:00:00+00:00
DR. MARIE DOBYNS:
Virchow, the father of hematology, identified the three factors responsible for vascular thrombosis, also known as blood clots: vessel injury, alteration in blood flow, and changes in the coagulability of the blood. Pregnancy affects all three factors. Your blood volume increases by a third when you are pregnant, and your body doesn't really know how to handle that without all of the mechanisms that occur between the placenta, the fetus, and the mother. If there is any issue that goes amiss within any of those three components, then the fetus won't develop properly.
The body responds to anything foreign that is going to upset the natural ebb and tide of life. Pregnancy is perceived as a hypercoagulable state. This is not a problem for most women; however, if you have a protein S or protein C deficiency, this upsets the hemostatic balance and the body responds by trying to protect the mother. That is why Tori had several miscarriages. Dr. Robert Stillman had a hunch and put Tori on an aspirin a day, which makes your blood thinner, enabling her to get pregnant. She was supplemented with progesterone suppositories in order to help the development of the fetus.
Tori initially went down to the Florida house and was under the care of Dr. Graham, a wonderful Jamaican physician. However, she retired during the sixth month of Tori's pregnancy. Dr. Marlow and I sent her to a specialist in Washington, DC, Dr. Bronsky He ran a series of blood tests, and her deficiency was eventually detected. However, the physicians had to find the exact balance for Tori, because the progesterone hormone can increase the chance of development of a blood clot. Therefore, once she got pregnant she took low molecular heparin shots because the progesterone put her at an increased risk for blood clots in the legs and lungs. The heparin shots kept her blood from getting too thick without interfering with the growth and development of the fetus and the placenta. An aspirin a day affects the clotting mechanism such that one who has protein S or protein C deficiency may get pregnant. However, once Tori was pregnant she had to be given heparin shots to thin her blood. She could not take the medication orally because that would have crossed into the placenta and harmed the fetus.
After the baby was delivered she went back to an aspirin a day, which is an antiplatelet drug that prevents the cells from clotting quickly. She also continued with the heparin shots until her levels balanced out. And because she was nursing Natashya, she couldn't take the oral form of the medication. An aspirin a day will decrease your incidence of stroke; also risk of thromboembolism will be drastically reduced with just an aspirin a day if you have this deficiency. Suffice it to say miracles do happen and blood is an amazing vehicle.
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